The bioanalytical analysis of anticancer agents established a more personalized treatment procedure. The importance of validating analytical procedures before they are put into normal usage is widely acknowledged. This novel approach has a lot of promise because it is quick, easy, and only requires a little amount of samples to get the accurate result. The goal of this mini review is to provide a comparative analysis of contemporary research on few anticancer agents and their methodology in reference to bioanalytical analysis. We provide practical approaches for determining extraction and clean up, precision and accuracy, selectivity and specificity, chromatographic analysis and its validation. We believe that the liquid chromatographic processes used in the bioanalysis of anticancer medicines, validation standards might have been applied in a variety of ways to counter the failure of an anticancer agent by increasing its therapeutic index approach.
In future cellular system, it is becoming more challenging to optimize the radio resource management and maximize the system capacity whilst meeting the required quality of service from user's point of view. Traditional schemes have approached this problem mainly focusing on resources within a cell and to large extent ignoring effects of multi-cell architecture. For multi-cell systems employing intra-cell orthogonal communication channels, inter-cell interference mitigation techniques are expected to be one of the key radio resource management functions. In this paper, we propose a multi-cell coordinated and un-coordinated dynamic resource sharing algorithms and reuse techniques among base station/ relay station cells. The sub carrier allocation and power allocation are performed on the basic of sum-rate maximization, by considering the load over the cell (3-sector cell). The simulation results show the performance comparison between both coordinated and un-coordinated resource allocation schemes with different sum-rate maximization algorithms.
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