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131Summary Large-scale breeding of Macaca jascicularis in the country of origin is a way in which the demands of the research community can be met whilst the feral population of monkeys is safeguarded. The establishment of the SICON-BREC project and the success of its breeding programme to date is clear evidence of the future trend in the supply of non-human primates for biomedical research.

The establishment of 3 specified-pathogen-free marmosets (Callithrix jacchus) during the period May 1969 to January 1973 is described. A brief history of the conventional breeding colony from which the animals were derived is given and hysterotomy and hand-rearing techniques are described.

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15 turnover studies in 8 pregnant rhesus monkeys using iodine‐labelled fibrinogen showed that fractional catabolic rates of this protein were similar to those in control females, whereas the absolute catabolic rates were significantly elevated. Intermediate, non‐clottable labelled breakdown products of fibrinogen were present in the circulation of these monkeys. The implication of these findings are briefly discussed.