Lean Six sigma (LSS) is the most widely used improvement strategy in almost all sectors. Initially it was started using in manufacturing and gained popularity across the sectors in short time. As most of the existing Lean Six sigma frameworks / strategies are specific to Manufacturing, Financial & IT sectors. This article presents Lean Six sigma specific tools and techniques relevant to the testing laboratory and the accreditation requirements as per the ISO 17025 standard. The study outlines the Lean Six sigma framework designed for integration in to the testing laboratory quality management system.