Characterization of Furoxancarbonitriles as a NewClass of Vasodilators. -The synthesis, structural characterization, NO-donor properties and in vitro vasodilating activities of the title compounds (II) and (IV) are reported. Some derivatives such as (IIa), (IId), and (IIe) are more potent vasodilating agents than the reference compound sodium nitroprusside. -(GASCO, A. M.; BOSCHI, D.; DI STILO, A.; MEDANA, C.; GASCO, A.; MARTORANA, P. A.; SCHOENAFINGER, K.; Arzneim.-Forsch. 48 (1998) 3, 212-218; Dip. Sci. Farm. Tecnol., Univ. Torino, I-10125 Torino, Italy; EN)
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Die Cyclopropenyliumperchlorate (I) reagieren mit KN3/Methanol zu den Aziden (II), die beim Erhitzen in die Triazine (III) übergehen; aus dem Salz (IV) entsteht das Triazin (V).
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