In patients with a surgical profile, the humoral link of the immune system was studied for the production of 3 classes of immunoglobulins (IgA, IgM, IgG), the formation of circulating immune complexes (CIC), bactericidal activity of blood serum (BASK) in comparison with the clinical picture of the disease. Serum immunoglobulins were determined according to Mancini, CEC by the conventional method according to D. K. Novikov (1987), BASK by the method of V. I. Nikitenko and O. V. Bukharin.

With the creation of new measuring instruments equipped with automation elements and powerful computer systems, the prospect of a qualitatively new level of laboratory diagnostics has arisen. Currently, large diagnostic laboratories are being equipped with equipment from well-known companies in Japan, USA, Germany, Austria, Switzerland. Research opportunities in the field of hematology, clinical biochemistry, immunology, microbiology have expanded significantly.