Background: Acute pancreatitis is a common disease with wide clinical variation and its incidence is increasing. Acute pancreatitis may vary in severity, from mild self-limiting pancreatic inflammation to pancreatic necrosis with life-threatening sequelae. Severity of acute pancreatitis is linked to the presence of systemic organ dysfunctions and/or necrotizing pancreatitis.
Background In the recent years, there has been a significant rise in the invasive candida infections. Epidemiological studies have demonstrated a shift in the trend of Candida species being isolated and their susceptibility patterns. The present study was carried out to evaluate the single institution experience of the burden of invasive candidemia. Methods This prospective study was carried out among 48 candida isolates from blood and urine samples among patients hospitalized in intensive care unit (ICU) for a period of two years. Gram staining, culture and anti-fungal susceptibility testing were carried out on all the samples. Results Highest occurrence of candidemia was in the age group of 41-60 years with a 50% male predominance. The case fatality rate among the study participants was 54%. Type 2 diabetes mellitus was a significant risk factor, with 45.8% of the candidemia patients being diabetic and 72.7% of the diabetics who developed candidemia expired (p value 0.035). In this study, 23% were Candida albicans and 77% non albicans species.
Background and Aim: NAFLD is a condition that is increasing dramatically in incidence and prevalence globally. There is known to be a direct relationship between conventional risk factors of metabolic syndrome and NAFLD. However, it is not a compulsion that these names risk factors will always be seen; it is, therefore, necessary to find investigations that could serve as predictive screening tests to catch the development of NAFLD in an individual at its earlier stages. OxLDL is a product of oxidative stress, and the circulating levels of the molecule seem to have possible risk predictor capability. With very little research previously conducted, the aim of the current study is to determine if there is a relationship between OxLDL and NAFLD. The study is limited to the Indian population. Method: A case-control study was conducted in a tertiary care teaching hospital; a total of 50 individuals were tested for circulating OxLDL levels. Of the tested subjects, 25 were patients with various stages of nonalcoholic liver disease, and 25 made up a control group of no liver pathology. Fasting blood samples were taken from all test subjects, and the serum underwent enzyme immunoassay to determine the OxLDL levels.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.