Δ 8 -THC acetate is a relatively new psychoactive cannabis product that is available online and in vape shops across the United States since it is currently largely unregulated. Because it contains a similar substructure to vitamin E acetate, which has been shown to form the poison gas ketene during vaping, we investigated potential ketene formation from Δ 8 -THC acetate, as well as two other cannabinoids acetates, CBN acetate and CBD acetate, under vaping conditions. Ketene was consistently observed in vaped condensates from all three cannabinoid acetates as well as from a commercial Δ 8 -THC acetate product purchased online.

No abstract

The rise of distinct subcultures of cannabinoid users and the proliferation of new psychoactive substances derived from the hemp plant reflects a dynamic relationship between the development of new cannabis products and the growth of the markets for these goods. This research combines social science and analytical chemistry framework to explore the historical, linguistic, and chemical developments of cannabis acetates and related products over time Understanding the multiplicity of contexts that have influenced the trajectory of moieties like THC-O-Acetate is an attempt at detecting and identifying other new psychoactive substances with structural or functional similarities to Δ⁹-THC through an interdisciplinary lens. The article concludes with a discussion on the potential implications of this kind of multidisciplinary research on new psychoactive substance research and regulation.

The rise of distinct subcultures of cannabinoid users and the proliferation of new psychoactive substances derived from the hemp plant reflects a dynamic relationship between the development of new cannabis products and the growth of the markets for these goods. This research combines social science and analytical chemistry framework to explore the historical, linguistic, and chemical developments of cannabis acetates and related products over time. Understanding the multiplicity of contexts that have influenced the trajectory of moieties like THC-O-Acetate is an attempt at detecting and identifying other new psychoactive substances with structural or functional similarities to Δ⁹-THC through an interdisciplinary lens.

Delta-8 THC acetate is a relatively new psychoactive cannabis product that is available online and in vape shops across the US since it is currently unregulated. Because it contains a similar substructure to vitamin E acetate, which has been shown to form the poison gas ketene during vaping, we investigated potential ketene formation from delta-8 THC acetate, as well as other cannabinoids acetates, CBN acetate and CBD acetate, under vaping conditions. Ketene was consistently observed in vaped condensates from all three acetates as well as from a commercial delta-8 THC acetate product purchased online.