Sera from 517 laboratory-housed nonhuman primates representing five genera and from 13 laboratory workers were examined for the presence of neutralizing antibodies to SA12 virus. The antibody prevalences were as follows: baboons, 66%; patas and vervet monkeys, 24%; macaques, 8%, and chimpanzees, 2%. The serum of one laboratory worker had antibodies. These results suggest that SA 12 virus is a common infection of nonhuman primates in laboratory colonies, especially baboons.

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The histopathological lesions induced by Filaroides cebus have been studied in seven capuchin monkeys (Cebus apella) without secondary infections and in eight capuchins dying from bacterial pneumonia of several types. The immediate parasitic injuries of the lung tissues consisted of mechanical disruptions and epithelial atrophy, the host responses of hyperplasia and metaplasia of the bronchiolar and bronchial epithelium as well as chronic interstitial inflammation resulting in interalveolar fibrosis. The importance of the Filaroides-induced lesions favoring secondary infections are discussed.

Marmosets (S. oedipus and S. fuscicollis) inoculated intravaginally with Herpesvirus hominis type 2 developed severe genital lesions followed by death. At necropsy, extensive hemorrhagic and necrotic lesions were observed in the urogenital tract. Four animals tested had BUN values of 98-220 mg/100 ml. Pathological and clinical observations suggest that the animals developed a uremia as a secondary complication of the genital herpes infection.

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