Purpose To reconstruct a 3D visualization from CT images of COVID-19 patients in order to improve understanding of the disease for better management and follow-up. Materials and methods We have retrieved CT images of 185 COVID-19 patients from the Cheikh Zaid International University Hospital in Rabat, Morocco. We then performed computer processing that allowed us to obtain a 3D visualization of these patients. Results In this article, we have chosen to do 3D reconstruction of three specific cases among 185 patients: - Cases (A1, A2) which are negative RT-PCR patient with normal CT images. - Cases (B1, B2) which are positive RT-PCR patient with abnormal CT images. - Case (C) which is a negative RT-PCR patient with CT abnormalities. To improve our results and have a better quality of the 3D reconstruction, we used different algorithms and a specific row data processing. Conclusion 3D reconstruction has a significant role in the diagnosis and management of COVID-19 patients. The quality and reliability of 3D reconstructions allow the clinician to make a quick and efficient diagnosis and avoid an eventual false negative (produced by the RT-PCR test). We suggest including chest 3D reconstruction in the patient management and prognosis evaluation.

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Introduction: Inherited restrictive cardiomyopathy (RCM) is a rare cause of RCM associated with cytoskeletal and sarcoma gene mutations. We describe a case of inherited RCM due to MYH7s genetic mutation.Case description: A 66 year-old-woman was admitted for acute global heart failure. She had a family history of RCM with a mutation of MYH7 gene: sons sudden death at 30, one of her daughters who is 40 and grandson who is 1. The transthoracic cardiac ultrasound (TTE) showed a bi-atrial dilation, a non-dilated left ventricle (LV) non-hypertrophied. Genetic investigation found the same pathogenic missense mutation (c. 1477A>G in heterozygous state) in our patient and her daughter who has a non-obstructive hypertrophy cardiomyopathy (HCM).A few weeks later, our patient had a syncope on complete atrioventricular block. A triple chamber pace maker was installed. Discussion: Familial RCMs mutations are characterized by high allelic, genetic and phenotypic variability, with autosomal dominant inheritance and variable penetrance. This mutation is rarely found in RCM, it is usually reported in HCM (OMIM 160760). Genetic screening should be considered to identify patients at risk in families with suspected familial transmission. MYH7 mutations seem to be associated with severe phenotypes, earlier age of onset and more pejorative evolution than other mutations. Conclusion:The evaluation of familial RCM requires an understanding of its variable phenotypic expression and incomplete penetrance. RCM and HCM may coexist in the same family. Genetic testing for hereditary RCM should be considered when secondary causes have been excluded.