The Oxalis corniculata (Oxalidaceae) is one of the most potential medicinal herbs and well known for multiple therapeutic properties (anti-inflammatory, anticancer, antioxidant, antimicrobial, analgesic and diuretic activity). This study investigated phytoconstituents, antibacterial activity and antioxidant activity of Oxalis corniculata leaves extract. Methanol based phytochemical screening of Oxalis corniculata revealed the presence of alkaloids, proteins, phenols, flavonoids, glycosides. The antibacterial activity revealed better potential inhibitory effect against gram-negative bacteria, particularly Escherichia coli and Salmonella typhi compared to Staphylococcus aureus, a gram-positive bacterium. However, 1% methanol extract showed highest antibacterial activity against Escherichia coli followed by Staphylococcus aureus and Salmonella typhi. Antioxidant activity of the methanol extract with 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging showed antioxidant activities with 3.87 µg/mL IC50 value. BIBECHANA 19 (2022) 27-33

The study the analyzed relationship of climate change with agricultural production in Kavre and Jumla districts. The specific objective of the study was to find out the dimension and linkage between agricultural production and climatic parameters in Kavre and Jumla. Time series data were analysed for the study. The data was sourced from the Department of Hydrology Meteorology, Department of Agriculture, and National Bureau of Statistics. Descriptive statistics, linear analysis test and back ward difference filter were the analytical tools used to determine the impact of climate change on productivity. During harvest period, the correlation of rice yield with temperature and rainfall was negative at Kavre but positive at Jumla. Similarly, the correlation of wheat yield with temperature and rainfall was positive at Kavre but negative at Jumla. The result showed that extreme fluctuation in weather caused negative impact on production in Jumla in compared to Kavre districts.