Introduction: Congenital bony fusion of the maxilla and mandible, especially as an isolated occurrence, is a rare condition while acquired fusion being even rarer. Case report: A rare case of a 32 year old female patient with acquired unilateral bony fusion between the zygomatic arch of maxilla and ramus of mandible is reported. Discussion: Forty one cases of syngnathia has been reported in the international literature from 1936 to 2009, of which 39 cases are congenital and two were acquired, case 1 probably as a result of a fibrotic tubed pedicle and in case 2 from myositis ossificans. According to several case series, bony ankylosis of the mandible and maxilla has also been found to occur in 30%-43% of cases of NOMA.