This paper presents a new voltage-mode single-input multiple-output multifunctional biquadratic filter using voltage differencing differential difference amplifiers (VDDDA) with high-input impedance. It consists of two VDDDA, two resistors, and two grounded capacitors. It can synthesize basic filter functions: high-past (HP), low-pass (LP) and band-pass (BP), responding through only single structure. The natural frequency can obtain by adjusting bias currents of VDDDA without disturbing quality factors. Because of using VDDDA as an active device in the circuit, the power consumption was low. The simulation using PSPICE program indicated that circuit operation has good agreement with the theory.