Red sea bream iridoviral disease (RSIVD) was first detected causing mass mortality among cultured red sea bream (Pagrus major) in the summer of 1990 in Japan. These viruses are genetically classified into three groups according to the nucleotide sequence of the major capsid protein gene. An outbreak of RSIVD often spreads from one net pen to adjacent pens. Transmission is by cohabitation, which is confirmed experimentally. This article discusses the diagnosis of the infection; pathology; pathophysiology; protective and control strategies against RSIVD.

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