This study focus on the current trend of prescribing of non-steroidal anti-inflammatory drug at a tertiary care teaching dental hospital in Jaipur. After taking permission from the Institutional Ethical Committee, this questionnaire study was carried out with the final year and intern students at tertiary care centre. Our study revealed paracetamol (41.4%) as the commonly prescribed analgesics followed by ibuprofen (24.5%). More than 60% of the respondents had good knowledge of contraindications to the use of these analgesics. Respondent’s knowledge regarding drug-drug interactions was fair. More than 70% were aware of interactions of diuretics and non-steroidal anti-inflammatory drugs, while about 95% correctly recognized the interaction of these analgesics with corticosteroids. Our study highlights the importance of knowledge of concurrent drug administration by the dentists to prevent adverse drug events.

Introduction: Considering the staggering number of drugs being prescribed to the patients for dental ailments, the ability of the dentists to recognize potential drug–drug interactions (DDIs) is essential to reduce their occurrence. This study aims to assess the dentist's ability to recognize the potentially clinically significant DDIs in clinical practice. Subjects and Methods: This questionnaire-based study was carried out among the dentists working at private tertiary care teaching dental hospitals in Jaipur city. Eighty-five dentists working as faculty members in various departments and having postgraduate degree in their respective specialty were enrolled after taking their written informed consent. A prevalidated close-ended questionnaire was given to the respondents to check their knowledge about common DDI possible in clinical dentistry practice. Statistical Analysis Used: Statistical analysis was done using descriptive statistics. Data were collected in a predesigned Microsoft Excel 2010. Continuous variables were presented as mean values ± standard deviation, and categorical variables were presented as percentages. Results: Among 85 dentists recruited for the study, no one had knowledge about all the common DDIs in dental practice. The participants could correctly identify only 47.86% of drug pairs. Drug information services available on the Internet were the most common source (32%) of knowledge of DDIs among them. Knowledge of the prescribed drug (40%) and complete drug history including over-the-counter and herbal products (35%) were the two important ways identified by them for avoiding unwanted drug interactions in clinics. Conclusion: The study revealed that the existing knowledge of the dentists was not adequate. Hence the knowledge of the dentists about DDIs pertinent to dentistry should be enriched and should be reinforced by arranging training sessions at constant intervals of time.

Background: This study aims to study the predictors and the pattern of adverse drug reactions to Covishield vaccine which is being used in the mass vaccination program of the Government of India. Methods: This cross-sectional questionnaire-based study was conducted among the dentists working as faculty in four different tertiary care centers in Jaipur city. A prevalidated questionnaire was circulated through E-mail/social media groups to all the participants. Results: A total of 574 participants fulfilled the questionnaire platform; however, six had been excluded from the study due to incompletely filled questionnaires. The remaining 568 were enrolled for the final analysis. About 296 (52.11%) were male and 272 (47.89%) were female. About 52.8% were in the age group of 31–49 years. About 87.32% of the enrolled participants had received both doses of Covishield. Most common postvaccination symptoms were fever (n = 145), local pain at injection site (n = 123), tenderness at injection site (n = 117), and fatigue (n = 91). Female gender, presence of comorbid diseases, and past coronavirus disease-19 infection were statistically significant risk factors for having adverse reactions post vaccination, P = 0.02, 0.043, and 0.0002, respectively. Conclusions: The data suggest that Covishield is well tolerated in the Indian population. Fever, local pain, tenderness at injection site, and fatigue are few commonly reported side effects. All the side effects were mild to moderate in terms of severity.

Background: Goiter is defined as the enlargement of the thyroid gland. This might be diffuse in nature nodular or multi-nodular. We planned a retrospective study of 100 histopathologically diagnosed thyroidectomy specimens and evaluated their frequency in relation to age and sex of the patients. Material and methods: The study was conducted in the department of Pathology at a tertiary care hospital in Jaipur city. The material included 100 thyroidectomy specimens. In case of thyroidectomy specimens, multiple sections were made up to thickness of 3 to 5 mm. The slice in which tumor appears closest to the resection margin was submitted entirely after dividing into adequate number of sections. All the lesions were grouped into benign and malignant lesions and were correlated to Age and Gender. Histomorphological evaluation of thyroidectomy lesions was done thoroughly to plan a better management of malignant lesions. Results: The female: male ratio of 4.2:1. The mean age of patients with thyroid diseases was 40.3 years and the peak incidence (34%) seen in the age group of 31- 40 years. Non-neoplastic cases accounted for 51% of the cases and neoplastic cases accounted for 49% of the cases. Conclusion: The thyroid gland may be affected with various disorders. Thyroidectomy may have both therapeutic and diagnostic value. Non- neoplastic disorders are more common. Females accounted for 81% of patients with thyroid lesions and the incidence peaked at third to fourth decade. Papillary carcinoma was the most frequent thyroid cancer and follicular adenoma was the common benign tumor

Cancer is a leading cause of death for children and adolescent worldwide. The cure rates in low middle-income countries are dismal (20%) in comparison to high income countries (80%). The first move is to assemble precise data on epidemiology of pediatric cancer across the country and its region wide variation. This study attempts to provide spectrum of pediatric malignancies from a tertiary care hospital in the state of Rajasthan, India. A total of 140 cases were studied retrospectively over a period of two years (April 2018-March 2020). Patients, 0-18 years of age that are diagnosed as a case of malignancy were included in this study. The records of these patients were retrieved and analyzed. Patients were stratified in 4 groups; 0-4 years, 5-9 years, 10-14 years and 15-18 years. Most of the patients fell in 15-18 year group (35.7%), followed by 5-9 year group (28.5%). Majority of cases, 67.8% were male. The male to female ratio is 2.1:1. Leukemia (40%) was the most common malignancy followed by lymphoma, retinoblastoma and malignant bone tumors. Acute lymphoblastic leukemia comprises majority (35/56) of leukemia. Retinoblastoma was predominant malignancy among <5-year children. In all other groups, leukemia was predominant. This study gauges the trend of pediatric malignancies at one of the largest tertiary care hospitals in Rajasthan, which is important in the planning and evaluation of health strategies. As we lack a dedicated pediatric cancer registry, such epidemiological studies play a significant part for this small but distinguished group of patients.