Infiltrating lipomatosis of the face has been described as a congenital disorder in which mature lipocytes invade adjacent tissues in the facial region. The presentation is always unilateral with hypertrophy of hard and soft structures on the affected side of the face. We present a case of a 27-year-old female who reported with a complaint of recurrent unilateral facial swelling with history of two previous resections, the histopathology or details of these surgeries were not available. The patient underwent resection of tumour and the histopathology confirmed it to be infiltrating lipomatosis. The surgery resulted in a definite improvement in the facial asymmetry and the patient is being closely followed up with no evidence of recurrence. The pathogenesis of the condition is unclear, though it has been postulated that the condition is at one end of a spectrum of overgrowth syndromes with classic Proteus syndrome on the other extreme. Management of this condition involves resection of the tumour which in most cases is subtotal to reduce the risk of damage to facial nerve. There is a controversy regarding both timing and extent of resection in the literature and we think the subtotal resection of tumour in an adolescent or older patient can give good aesthetic outcome without compromising facial nerve function. However, the patients should be informed about high rate of recurrence and increase risk of complications with any subsequent surgery.
Fine Needle Aspiration Cytology is known to be quick, simple and effective way of diagnosing Breast Lumps since long. It is also a very good financial alternative to the surgical biopsy. This study was undertaken with the aim to calculate sensitivity and specificity of fine needle aspiration cytology as diagnostic method by correlating it with histopathological findings. This was a retrospective study done in department of pathology, Maharaja Agrasen Medical College from Sept. 2007 to April 2012. Fine Needle Aspiration Cytology was performed on 454 cases of Breast lumps and out of these, 56 cases were received in the department for histopathological examination. We categorized the lesions as Inflammatory, Benign, Atypical, Suspicious and Malignant on Fine Needle Aspiration and compared the result with the histological findings. We found that sensitivity and specificity of Fine Needle Aspiration were 96.42% and 100% respectively in identifying Benign and Malignant Breast Lumps. In conclusion, we found that Fine Needle Aspiration Cytology is very efficacious, simple, easy and cost effective method in diagnosing breast lumps.
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