Nanohybrid systems combining both persistent luminescence and magnetic property are recent breakthroughs in novel multimodal imaging and cancer therapy; however, integrating strategies at a common platform is complex. Herein, we report the synthesis of a Gd3Al5−xGaxO12:Ce3+,Pr3+ (GAGG:Ce,Pr) nanophosphor (x = 1–5) with simultaneous paramagnetic/persistence luminescence via a simple tartaric acid assisted solgel synthesis. Structural analysis revealed the formation of a pure cubic garnet crystal of GAGG:Ce,Pr, which expanded linearly upon gallium incorporation. Moreover, the novel paramagnetic/persistence luminescent material showed the formation of nanoparticles with excellent colloidal stability. Photoluminescence emission analysis showed a broad emission band in the range of λ = 500–750 nm attributed to (5d → 4f) transitions of Ce3+ and a sharp peak centered at λ = 612 nm attributed to electronic transitions (1D2 → 3H4) within Pr3+ upon blue light excitation. In particular, GAGG:Ce-Pr sample with Al:Ga ratio 1:4 yielded persistent luminescence upon blue, UV, and white light excitation at room temperature. Additionally, GAGG:Ce-Pr (x = 4) nanophosphor was paramagnetic and also showed signs of weak ferromagnetism at ambient temperature. Cellular toxicity analysis in different cell lines revealed the relatively safe nature of nanoparticles at the tested concentrations. Overall, in our preliminary analysis, GAGG:Ce-Pr (x = 4) showed the persistent optomagnetic property and low cellular toxicity for potential utilization in multimodal theranostic applications.

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Aluminum (Al) is the most abundant metallic element and constitutes about 8% of the earth's crust. The aluminium is related to different neurological disorders like Alzheimer's, bipolar, depression, etc. As well as anemia, also reduces the absorption of calcium causing pain, deformities and broken bones.1-2 The development of nanotechnology has led to a growing interest in the study and design of nanosensors, in order to improve selectivity, limit of detection, reproducibility and durability of the current sensors.4-5 In this paper is repoted the preparation of  hybrid material based on platinum nanoparticles (NP Pt) on  multiwall carbon nanotubes (MWCNT) prepared by inverse microemulsion method using sodium dodecyl sulfate (SDS) as surfactant in a mixture of hexane/isopropanol/water. The hybrid material was characterized by transmission electron microscopy (TEM). The hybrid material showed small spherical nanoparticles with average sizes of 2.15±0.54 nm, well as thermogravimetric analysis  a load of 20% platinum. The NP Pt/MWCNT hybrid material use for determining Al+3 using dopamine as a chelating molecule for the indirect determination of the aluminum by differential pulse voltammetry in neutral medium. Under optimal experimental conditions it was determined the sensitivity of the NP Pt/ MWCNT sensor was 27.75 μA/ppb  Al+3 with a  linear response range from 0 up to 15 ppb Al3+. References 1. C. Exley, Environ Sci: Process Impacts, 15, 1807, (2013). 2. WHO (World Health Organization), Safety  evaluation of certain food additives and contaminants, p.173, WHO, Geneva, 2007. 3. R. L. McCreery, , Chem. Rev. 108, 2646 (2008). 4. A. Hayat, G. Catanante, J. Louis Marty,  Sensors, 14, 23439 (2014). Figure 1