<p><strong>Objective: </strong>The aim of this study was to evaluate the effect of different surface clinical treatments on the roughness (Ra) of a lithium disilicate ceramic veneer. <strong>Material and Methods: </strong>Forty-eight lithium disilicate discs with ceramic veneer and glaze layer were manufactured and distributed into six groups (n=8) according to the surface treatment performed: G1, glaze layer (control group); G2, diamond bur 4138F; G3, diamond bur 4138F + 4138FF; G4, diamond bur 4138F + new glaze layer; G5, diamond bur 4138F + ceramic polishing kit; G6, diamond bur 4138F + rubber cup with diamond paste + felt with diamond paste. Surface Ra measurement (µm) was performed using a profilometer before and after surface treatments, and one specimen from each group was subjected to Scanning Electron Microscopy (SEM) after treatment. Two-way ANOVA and Tukey's test (5%) were used for data analysis. <strong>Results: </strong>Group 2 (3,00 ± 0,61)<sup>b</sup> showed higher values of Ra, followed by Group 3 (1,93 ± 0,45)<sup>c</sup>, Group 6 (1,56 ± 0,22)<sup>ac</sup>, Group 5 (1,14 ± 0,68)<sup>a</sup> and Group 4 (0,90 ± 0,26)<sup>a</sup>. G4, G5 and G6 were not different between each other and control group (1,11 ± 0,21)<sup>a</sup>. SEM imaging revealed surface smoothness in G1, G4 and G5, and presence of irregularities in G2, G3 and G6. <strong>Conclusion: </strong>it is possible to conclude that different surface clinical treatments influences the roughness of a lithium disilicate ceramic veneer.</p><p> </p><p><strong>Keywords</strong><strong>:</strong> Ceramics; Dental porcelain; Dental polishing.</p>