CD is a relatively common occupational skin disease in human beings, but the prevalence in veterinary medicine is undefined. It can lead to debilitating clinical signs. Further research in human medicine and even more so in veterinary patients, will be required in order to allow for an evidence-based approach in its diagnosis and management.

This study demonstrated that MS and MR S. pseudintermedius isolates were equally susceptible to rifampicin and that dosing intervals should be designed for time-dependent efficacy. These data can support pharmacokinetic studies of RFP in dogs with susceptible infections caused by S. pseudintermedius.

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Purpose This study introduces a standardized 2-plane approach using 8 landmarks to assess alveolar bone levels in mice using micro-computed tomography. Materials and Methods Bone level differences were described as distance from the cemento-enamel junction (CEJ) to alveolar bone crest (ABC) and as percentages of vertical bone height and vertical bone loss, comparing mice infected with Porphyromonas gingivalis (Pg) to controls. Eight measurements were obtained per tooth: 2 in the sagittal plane (mesial and distal) and 6 in the coronal plane (mesiobuccal, middle-buccal, distobuccal, mesiolingual, middle-lingual, and distolingual). Results Significant differences in the CEJ-to-ABC distance between Pg-infected mice and controls were found in the coronal plane (middle-lingual, mesiobuccal, and distolingual for the first molar; and mesiobuccal, middle-buccal, and distolingual for the second molar). In the sagittal plane, the distal measurement of the second molar was different. The middle-buccal, mesiobuccal, and distolingual sites of the first and second molars showed vertical bone loss relative to controls; the second molar middle-lingual site was also different. In the sagittal plane, the mesial sites of the first and second molars and the distal site of the second molar showed loss. Significantly different vertical bone height percentages were found for the mesial and distal sites of the second molar (sagittal plane) and the middle-lingual and distolingual sites of the first molar(coronal plane). Conclusion A reliable, standardized technique for linear periodontal assessments in mice is described. Alveolar bone loss occurred mostly on the lingual surface of the coronal plane, which is often omitted in studies.

A two-year-old male castrated Shiba Inu with atopic dermatitis presented to the Small Animal Teaching Hospital with a one-month history of swelling, lameness and crusting on the plantar aspect of the paw of the left hindlimb. At presentation, he was receiving subcutaneous injections of allergen-specific immunotherapy and oral ciclosporin at 4.3 mg/kg daily for the past 8 and 19 months, respectively. Tissue aerobic culture and susceptibility revealed Nocardia species susceptible to multiple antimicrobials. This dog was treated with topical antiseptic and sulphadimethoxine/ormetoprim (Primor). The swelling improved after one week and the dermatological lesions resolved after three months. Fifteen months after resolution of the nocardiosis infection the dog remains in remission. This is a case report describing the successful medical management of cutaneous nocardiosis in a dog with atopic dermatitis receiving daily oral ciclosporin therapy.