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Although positive peer relationships have been shown to promote healthy school involvement and academic achievement, subpopulations of perceived popular (i.e., socially prominent, high status), but aggressive, youth have been identified who exhibit poor school functioning. The objective of this study was to examine whether attainment of perceived popularity may be a contributing factor in the school difficulties of these aggressive youth. Data were collected from 208 early adolescents (95 boys; 113 girls) during the fall and spring of their fourth- and fifth-grade years. Latent growth curve analyses indicated that, for children with above-average levels of aggression, perceived popularity predicts trajectories of increasing school avoidance and declining academic performance. These results were significant even after accounting for how integrated children were in their social network (i.e., how many friends they had), providing further support to the contention that for aggressive youth, social status serves as a risk factor for school maladjustment.

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Prenatal cocaine exposure may affect developing stress response systems in youth, potentially creating risk for substance use in adolescence. Further, pathways from prenatal risk to future substance use may differ for girls versus boys. The present longitudinal study examined multiple biobehavioral measures, including heart rate, blood pressure, emotion, and salivary cortisol and salivary alpha amylase (sAA), in response to a stressor in 193 low-income 14- to 17-year-olds, half of whom were prenatally cocaine exposed (PCE). Youth’s lifetime substance use was assessed with self-report, interview, and urine toxicology/breathalyzer at Time 1 and at Time 2 (6–12 months later). PCExGender interactions were found predicting anxiety, anger, and sadness responses to the stressor, with PCE girls showing heightened responses as compared to PCE boys on these indicators. Stress Response × Gender interactions were found predicting Time 2 substance use in youth (controlling for Time 1 use) for sAA and sadness; for girls, heightened sadness responses predicted substance use, but for boys, dampened sAA responses predicted substance use. Findings suggest distinct biobehavioral stress response risk profiles for boys and girls, with heightened arousal for girls and blunted arousal for boys associated with prenatal risk and future substance use outcomes.

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