Radiologic and clinical indicators of periodontal destruction were increased in individuals with poorly controlled T2D. Low SES aggravated the periodontal condition in individuals with T2D.
The hypothesis was rejected, as the statistical results indicated that there were significant differences between virtually planned implants' position and the final position of implants placed clinically.
Statistically significant differences were observed in positions between the implant replicas in the pre-operative plaster models created from a CAD/CAM surgical template and the implant replicas in the post-operative plaster models that were made from patients' impressions taken at ≥1-year follow-up. Due to the lack of reference objects in the pre- and post-operative working casts, additional refinements are required in order to validate the impression matching method and recommend the method to be used.
Purposes-The aim of this study was to investigate the relation between plasma level of glutamate and extent of radiographic bone erosion of the TMJ in patients with early RA in relation to inflammatory disease activity as well as estradiol and testosterone.Patients and Methods-47 patients (29 women and 18 men) of whom 24 were seropositive were included shortly after being diagnosed with RA. Radiographic signs of bone tissue resorption (erosions) in the TMJ was recorded by cone-beam CT images and an erosion score (0 -24) was calculated for each patient. Venous blood was analyzed for rheumatoid factor, C-reactive protein, erythrocyte sedimentation rate, leukocyte particle count, glutamate, estradiol and testosterone. Nonparametric and parametric statistical methods were used in the analysis when applicable.Results-Resorptive changes of the TMJ were found in a major part of the patients. There was a significant positive correlation between plasma level of glutamate and extension of radiographic erosions that was strongest in the patients with low levels of C-reactive protein, estradiol or testosterone. On the other hand erosions were correlated with C-reactive protein in patients with high levels of estradiol. The highest levels of glutamate were found in patients with low levels of C-reactive protein and estradiol.Conclusion-This study shows that a majority of patients with early RA presents radiographic signs of bone tissue resorption of the TMJ and that circulating glutamate is associated with the extent of these changes. The relationship between glutamate and bone resorption seems to be influenced by systemic inflammatory activity as well as estradiol and testosterone levels.
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