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Summary.-In a previous report we have shown that a few substances, especially thiouracil, are incorporated as false precursors into melanin during its synthesis.In the present investigation, we have intensified our studies on the incoporation of thiouracil into melanotic melanomas. Firstly, the distribution and retention of both 14C-and 35S -labelled thiouracil in mice with transplanted melanomas were studied.

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