No abstract

Pleomorphic adenoma, a common salivary gland tumor, is a rare benign breast tumor. It doesn't have specific features and its diagnosis can be made on the final histopathological examination. There have been reported few cases of malignant transformation and many recurrences, therefore it is required an adequate excision of this tumor with clear margins. We present the case of a woman of 47 years old, who was admitted in our Department for a right perimamelonar lump, with uncertain imaging features. A right mammary segmentectomy was performed and the routine histopathological and immunohistochemical examination led to the diagnosis of pleomorphic adenoma of the breast.

Malignant melanoma (MM) has been shown to metastasize with relative affinity to the gastro-intestinal (GI) tract, especially through the small intestine, mostly within, but also later than the first 5 years after initial diagnosis. MM appears to less often originate in the GI tract. Surgical excision is reported to be safe and capable of improving oncological outcomes in the absence of other metastatic disease. We hereby report the case of a patient without a history of MM presenting in our clinic with severe anemia due to a tumor located in the small bowel diagnosed on abdominal tomography. Surgery consisted in a radical resection of the affected small bowel segment. Pathological examination revealed a MM metastasis to the jejunum. On further investigation of the patient, a cutaneous lesion suggestive of MM was identified on his right upper limb, which was excised, and the patient has been referred to the multidisciplinary team for initiation of adjuvant chemotherapy. Further follow-up is required due to MM's propensity for multiple metastases. This case emphasizes the fact that in a patient diagnosed with an intestinal tumor a thorough clinical examination should be performed, as one of the possible differential diagnosis of intestinal tumors is the metastatic localization of a cutaneous MM.