Objectives: Evidence for complementary therapies as important strategies to relieve cancer treatment-associated symptoms is increasing. Mostly, these complementary therapies start at the end of adjuvant treatments, resulting in a long delay until the well-being of patients is addressed. Further, long distances between the rehabilitation center and the patients' residence hinder patients' compliance. Methods: The multimodal outpatient LOTUS Care Cure Project (LCCP) was tested in a randomized controlled trial including patients of various cancer entities and stages while on adjuvant chemotherapy and/or radiotherapy or outpatient aftercare. The intervention group received the LCCP additionally to the conventional treatment (LCCP group, n = 50). The control group (CG) was split into 2 groups, with (CG1, n = 33) and without (CG2, n = 17) weekly talks. The primary endpoint was quality of life (QoL) after 3 months. Results: In the LCCP group, QoL significantly improved after 3 months compared to CG2 (p = 0.022) but not compared to CG1. Other parameters showing a significant improvement were cognitive (p < 0.05, vs. CG1 and CG2) and social function (p < 0.05, vs. CG2). Conclusions: This pilot study describes a multimodal outpatient complementary therapy program conducted in parallel with conventional therapies and its potential to significantly improve QoL and reduce treatment-associated side effects. To substantiate these data, multicenter trials are needed.

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In the study, patients were questioned about compliance, tolerance and subjective assessment of lactic acid containing food. In the first part of the questioning, 30 patients with gastroenteropathy or dermopathy took 200 ml of the lactic acid containing food every day during a period of 6 months. In the second part, 70 patients have been prescribed the lactic acid containing food independent of an indication for a period of more than one month. In addition, it was recommended to carry on with taking the lactic acid containing food after the treatment in hospital. 4 weeks after they left the hospital, the patients were asked questions about taking the lactic acid containing food on the telephone. The results are presented and discussed.

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