Introduction: Maintaining oral health becomes a challenge when Alzheimer's disease progresses to the intermediate and late stages. Objective: To analyze the literature on Alzheimer's disease and its relationship with dentistry in high impact journals, with a focus on etiology, diagnostic methods, treatment, dental clinical characteristics and dental management. Methodology: The search was carried out in the databases PubMed, SCOPUS and Google Scholar, using the terms "Alzheimer's", "etiology", "diagnostic methods", "treatment", "dental clinical characteristics" and "dental management", together with logical Boolean operators OR and AND. Results: It is important to know that the etiology of Alzheimer's disease is uncertain; the most widely used diagnostic methods for this disease are biomarkers. There is no drug capable of alleviating Alzheimer's disease. It is very common to find different oral diseases due to the lack of hygiene presented by patients suffering from Alzheimer's disease, so it is important to give education to their caregivers to perform oral hygiene. Conclusion: Currently, the issue of the effects of Alzheimer's disease on dentistry has been neglected. It is important to pay more attention to it and to educate caregivers about the possible oral diseases involved in the future as a consequence of poor oral care.

COVID-19 pandemic has caused a sudden significant increase in hospitalizations for pneumonia with multiorgan disease. Objective: To analyze the literature on SARS-CoV-2 and its impact today, in high-impact journals. Methodology: The search was carried out in Pubmed, Google Scholar, using the terms of "COVID-19", "SARS-CoV-2", "immune response", "transmission routes", "oral manifestations", "treatment", "diagnosis" in conjunction with logical boolean operators OR, AND. Results:The innate and adaptive immune response are the key to the clinical progress of the infection, transmission is through droplets that are suspended in the air, which goes from the moment a person speaks, coughs or sneezes. Clinical diagnostic test for the detection most widely accepted is the PCR test. Loss of taste is an oral manifestation that is frequently seen in people who are infected with SARS-CoV-2. Conclusion:The immune response is an important issue to address due to the relationship that SARS-CoV-2 has with the immune system, therefore, it is of utmost importance that there is an effective treatment against SARS-CoV-2.