Aim
The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes.
Methods
In 2014-2015, 976 colonoscopy was performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group, we documented the relationship between HbA1C and the occurrence of polyps high-grade dysplasia, and colon cancer. The data were statistically analyzed.
Result
1) Patients with diabetes have a higher frequency of polyps with high-grade dysplasia/ carcinoma - (32/91 (35.16%) in comparison to patients without diabetes 136/885 (15.37%), p <0.001.
2) Patients with diabetes have a higher frequency of polyps with cancer - (9/91 (9.89%) as compared to patients without diabetes in patients 18/885 (2.03%), p <0.001.
3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (p = 0.022)
Conclusion
The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to the conclusion that diabetic patients are at a higher risk of developing colorectal cancer thus requiring more need for a controlled colonoscopy. Therefore it may be worth to consider a scheme for screening patients in the group mentioned above by performing colonoscopy.
IntroductionThe ESPEN guidelines on long-term (> 3 months) parenteral nutrition recommend the use of tunnelled central venous catheters (CVCs) to minimise the risk of insertion site infection. A developed symptomatic infection of the soft tissue tunnel surrounding a CVC may rapidly become directly life threatening if the infection progresses along the catheter tunnel towards its end inserted into the venous system. This requires immediate management to eliminate infection and limit its effects.AimTo compare two surgical techniques for the treatment of suppurative inflammation of a CVC tunnel: conventional drainage of the infected tissues (surgical technique A) vs. radical en bloc excision of the infected tissues together with the infected central catheter (surgical technique B).Material and methodsSeventy-three patients hospitalised due to CVC tunnel phlegmon between April 2004 and May 2014 were included in the retrospective study. Thirty-four (46.5%) patients underwent surgical procedure A and another 39 (53.5%) underwent procedure B.ResultsThe mean duration of antibiotic therapy following procedure A was 8 ±3 days, whereas procedure B required 7 ±2 days of antibiotic therapy (NS). The mean hospitalisation period following procedure B was over 8 days shorter in comparison to that following procedure A (16.54 ±7.59 vs. 24.87 ±10.19, p = 0.009, respectively).ConclusionsThe surgical treatment of CVC tunnel phlegmon involving radical en bloc excision of suppurated tissues along with the infected CVC shortens hospitalisation, expedites the insertion of a new CVC, and potentially reduces treatment costs.
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