Alcoholism is prevalent throughout the Americas, it affects an average of 10% of the population, therefore it can be considered a public health problem. Alcohol abuse can cause several injuries to the metabolism, being responsible for causing liver damage and other complications. Zieve's syndrome (ZS) is considered an example of these insults, it represents a rare condition and is generally underdiagnosed in clinical practice. The rarity of this syndrome means that patients are often submitted to unnecessary exams due to the lack of knowledge of this possible diagnosis by the medical team. It should be suspected whenever there is anemia, elevation of indirect bilirubin and secondary hyperlipidemia in the context of acute and abusive alcohol intake, without any obvious sign of gastrointestinal bleeding. In this article we discuss a case report about ZS of a patient attended at a metropolitan hospital in Belo Horizonte.

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