Bone loss caused by periodontitis can be potentiated by diabetes. Atorvastatin (ATV), has been tested in periodontitis due to its anti-inflammatory and antiresorptive activities, but it has been reported to increase the risk of diabetes. Therefore, this study aimed to evaluate the effect of ATV on alveolar bone of rats with periodontitis and diabetes. For this, 72 Wistar rats were divided into 4 groups: Naïve (N), experimental periodontitis (EP), diabetes mellitus (DM) and ATV. DM was induced by streptozotocin (60 mg/kg-ip.), after 12 hours fasting. Following, all animals were submitted to EP. ATV was administered (27 mg/kg, v.o.) 30 minutes before ligature and daily until the 11th day. Animals from N group did not undergo any intervention. After 11 days of EP, all animals had their glycemic rate measured and then were euthanized. Maxillae were collected for macroscopic, micro-tomographic and microscopic analyses. DM caused intense bone loss (60%) marked by reduction on trabecular thickness and bone volume (p<0.05). It was seen a significant reduction on osteoblast with increase on osteoclast counts, as well as, inflammatory infiltrate in the periodontium. ATV was not able to protect bone, improving bone loss by 21%. ATV caused a significant increase (20%) on blood glucose levels. In summary, ATV did not protect alveolar bone loss and did not modulate the inflammation in DM animals submitted to EP. ATV increase of blood glucose levels in these animals. Therefore, the systemic use of ATV in non-controlled diabetic conditions should be carefully evaluated.

access to clean water and sanitation. High prevalence of malnutrition, anemia and growth stunting resulted in several nutritional interventions. Finally, a sustained prevalence of disease despite improved infrastructure highlighted the need for behavioural interventions and a health curriculum. Outcome & Evaluation: Between 2007-2015, the prevalence of malnutrition and growth stunting declined (height: 30.9% <3 rd percentile to 17.0% 5 th percentile, weight: 10.3% <3 rd percentile to 7.6% 5 th percentile). Similarly, scabies dropped from 35.2% to 7.2%. The prevalence of intestinal helminths slightly increased to 7.2% from 6.6%. In 2015, fifty-nine of the 517 students required further treatment and were referred to local physicians in a nearby village, sustainably engaging the population with the medical system. Going Forward: Physical exams proved to be an invaluable tool. They will continue to guide and evaluate interventions, and screen for students requiring urgent treatment until permanent local medical staff is employed. The unique bond between volunteers and students has been essential to the continued success of the project. Eager to return, all 2015 volunteers have become leaders for 2016, and will focus on the completion of water and sanitation systems and the sustainable implementation of the health curriculum.