Objective: There is no common concencus the clinical results of coronary artery bypass grafting (CABG) surgery patients who underwent off-pump or conventional techniques. Our aim of this study was to compare the changes of myocardial functions, patients' clinical results, biochemical marker release during surgery and postoperatively in On-and Off-Pump CABG surgery. Method: A consecutive series of 50 coronary artery disease (CAD) patients who underwent elective CABG surgery included for this study. The patients were divided into two groups (Group 1, N = 25 and group 2, N = 25). Demographic data including the patients' age, gender, body mass index (BMI), diseased coronary artery numbers, LVEF were similar. Postoperative red package blood cell, fresh frozen plasma, and thrombocyte requirements were high in On-Pump group (p < 0.05). But there was not any significant difference when compared the number of unexpected surgery because of mediastinal bleeding after operations in both groups. Preoperative and postoperative N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP), cardiac Troponin-I (cTnI) levels during and after surgery, and left ventricular ejection fractions (LVEF) prior to discharge from hospital were compared. Results: There were no statistical significancy when compared postoperative mortality and morbidity. The operations time was low in off-pump group (p < 0.05). The NT-proBNP levels were similar in both groups (p > 0.05). However, cTnI levels were significantly higher in the on-pump group (p = 0.0001). Postoperative LVEF decreased significantly in both groups when compared to preoperative echocardiography examinations (p = 0.001). But the changes of postoperative LVEFs in both groups were not statistical significant (p > 0.05). Conclusion: Our study results indicated that cardiac enzyme release was high after On-Pump CABG surgery. However, LVEF decreased in both techniques. There were some advantages of OPCAB operations such as decrease of inflammatory responses and angina pectoris incidence due to extracorporeal circulation; however, these techniques did not affect postoperative mortality and morbidity. Therefore, in selected cases to provide longer operation time, Off-Pump CABG could be used but it has no superiority over On-Pump CABG surgery.

Background: The new onset of atrial fibrillation (NOAF) can be occurred after coronary artery bypass grafting (CABG) surgery. NOAF can be occurred because of postoperative severe hemodynamic instability, long duration of ICU and hospital staying time, morbidity and mortality. Our aim of this study was to investigate whether N-terminal pro-brain natriuretic peptide (NT-proBNP) is a cause of NOAF after CABG. Methods: Forty CABG patients were enrolled for this study. Twenty patients operated on cardiopulmonary bypass (Group I; n: 20). The remaining patients have operated using a beating heart technique (Group II; n: 20). The NT-proBNP levels were calculated preand postoperatively. Results: High rate of NOAF was detected in group I patients (P < 0.05). In both groups, the NT-proBNP levels were low with sinus rhythm. The NT-proBNP blood levels in different times (T1, T2, T3, T4) among Group I were found higher than Group II. Conclusions: Our research demonstrated that there was a strongly close relationship between blood NT-proBNP levels' and atrial fibrillation occurrence in CABG patients. According to our results to detect postoperative AF development in early time and its treatment, blood NT-proBNP levels can be calculated in those patients for reducing morbidity and mortality due to AF.