Over the past decade a rapidly growing number of persons with primary obesity due to availability of different foods and the automation of life [1]. Regular consumption of highcalorie and, in particular, food rich fast (simple) carbohydrates and a sedentary lifestyle, lead to an increase in the blood level of postprandial glycemia, development of insulin resistance and, as a consequence, the development of diabetes mellitus (DM) type 2 [2].In the process of phylogenesis the human body was formed in the conditions of consumption number of meals equivalent consumed energy [3][4][5]. It is known that the consumption of food, not only compensates energy expenses, but also improves the psychological state of the person through the production of biologically active substances that have a morphine effect (mild euphoria and quite often with a food addiction) [6][7][8].A factor that is fundamental in the development of primary obesity is alimentary. It is proved that the obesity is manifested in childhood and pubertal periods of life, is a predictor of the formation in adulthood metabolic syndrome, early atherosclerosis, insulin resistance, DM type 2 and its associated vascular complications, and an increased risk of developing cancer [9][10][11][12][13][14][15].Objective: to study carbohydrate metabolism in young women with primary obesity. Methods: the study involved 241 women of young age (16 -45 years) (mean age of 28.5 ± 7 years) with primary obesity (body mass index of 26 to 62 kg/m 2 ). All patients were divided into groups depending on the age of onset of increase of body weight: I groupindividuals with obesity manifested in childhood and puberty (n = 164), mean age (26 ± 7,5) years and II group, persons whose obesity developed in the post-pubertal period (n = 77), mean age (31 ± 8) years.The degree of obesity was determined by body mass index (BMI) according to who criteria [16], the type of obesity was assessed according to the generally accepted index of the ratio of waist size to hip size (ON/ABOUT) [17, 18]. Gynoid or Android type of obesity was determined according to the criteria of NCEP -ATP III (National Cholesterol Education Program -Adult Treatment Panel III), given that the normal ratio for women is no more than 0.85 [19].Assessment of glucose homeostasis was performed according to the recommendations of the American diabetes Association 2012 [20]. The blood glucose level on an empty stomach (Glu 0) (mmol/l) and in the standard oral test glucose tolerance (OTG), which was carried out in 30 (Glu30), 60 (Glu 60), 90 (Glu 90) and 120 (Glu 120) standard min after load of 75 g glucose was determined in plasma of capillary blood glucose oxydase method using analyzer "Biosen C-line" (EKF, Germany).Evaluation of the results OTTG was conducted in accordance with WHO recommendations.Determination of glycosylated hemoglobin HbAc1 in blood (%) was determined by a photocolorimetric method using a commercial kit of reagents JSC "Reagent" on the photoelectric photometer KFK-3.To calculate the content of insulin in t...

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