This descriptive associative study focused on work-related factors as determinants of selfefficacy and resilience among 58 purposively-sampled Child Development Workers (CDWs). It specifically aims to profile the CDWs based on various work-related variables, to determine their psychosocial needs, resources, levels of self-efficacy and resilience, and to verify the association and relationship of these variables in relation to self-efficacy and resilience. A questionnaire, comprised of questions on perceived needs and resources and work-related aspects, a modified version of Bandura's (2006) Teacher Self-Efficacy Scale, and Smith et al.'s (2008) Brief Resilience Scale, were group administered to the participants. Thereafter, results were analyzed using descriptive and correlation statistics. Results showed that respondents were divided almost equally between the low-and high-scoring groups in both self-efficacy and resilience. Notably, respondents' resilience and self-efficacy mean scores were relatively higher than the expected average score. Correlation further revealed moderate positive relationship between self-efficacy and resilience (r = 0.333). In terms of work-related factors, many of those with high self-efficacy and high resilience scores reported also having: (a) supportive barangay officials, (b) cooperative day care children's parents, (c) satisfaction with pupils, (d) job satisfaction, and (e) life satisfaction in general. As a conclusion, the majority of the 58 selected CDWs reported satisfaction in work-related factors related to the children they cater to, and also work and life in general. In addition, CDWs who had high scores in selfefficacy and resilience reported having support, cooperation and satisfaction.