Objective: The purpose was to examine the associations among body weight status, blood pressure and daily Na intake among grade 7 students from south-western Ontario, Canada. Design: Cross-sectional. Data were collected using the Food Behaviour Questionnaire, including a 24 h diet recall. Measured height and weight were used to determine BMI. Blood pressure was taken manually using mercury sphygmomanometers. Setting: Twenty-six schools in south-western Ontario, Canada. Subjects: Grade 7 students (n 1068). Results: Body weight status indicated 1 % were underweight, 56 % normal weight, 23 % overweight and 20 % were obese. Mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 108?3 (SD 10?3) mmHg and 66?0 (SD 7?5) mmHg, respectively, and mean Na intake was 2799 (SD 1539) mg/d. Bivariate analyses suggested that SBP (P , 0?001) and DBP (P , 0?001) were significantly different by body weight status, yet no associations were observed for Na. Adjusted for gender, ethnicity and under-reporting, participants were more likely to be overweight/obese if they had higher SBP (v. lower: OR 5 1?06, 95 % CI 1?05, 1?08, P , 0?001), higher DBP (v. lower: OR 5 1?02, 95 % CI 1?00, 1?04, P 5 0?043) and higher intakes of Na (3rd v. 1st quartile: OR 5 1?72, 95 % CI 1?14, 2?59, P 5 0?009; 4th v. 1st quartile: OR 5 2?88, 95 % CI, 1?76, 4?73, P , 0?001). Conclusions: High intakes of Na, coupled with high SBP and DBP, were associated with overweight and obesity status among the grade 7 sample from south-western Ontario, Canada.

The purpose of this study was to determine the associations among evening snacking (food choices, portion sizes), afterschool-evening screen time, overall diet quality, and weight status. Participants consisted of 1008 young adolescents (secondary analyses, n = 651) from schools in Windsor-Essex, Ontario. The Web-based Food Behaviour Questionnaire, including a 24-h diet recall, was used to assess eating and screen time behaviours (television and video and computer games), as well as nutrient intake; height and weight for BMI were measured using a stadiometer. Results indicated that the majority of participants (62%) consumed an evening snack that contributed approximately 11% of their daily caloric intake. Evening snacking was associated with an overall good diet quality compared with that of non-evening snackers (p < 0.001). Increased afterschool-evening screen time was associated with fewer evening snack servings of vegetables and fruit (p < 0.05) and an overall increase in evening snack food portion sizes (p < 0.001). After accounting for other evening snacking factors, participants with greater than 6 h of afterschool-evening screen time were less likely to have a good overall diet quality compared with those with less than 1 h of afterschool-evening screen time. Therefore, increased screen time, because it is associated with greater evening snack portion sizes and overall poor diet quality, is of great concern regarding young adolescents' evening behaviour.

AimsMicronodular thymoma with lymphoid stroma is a rare subtype of thymoma with characteristic clinical and pathological features. Some of the features, such as indolent nature, principally spindle morphology and no significant association to myasthenia gravis, are shared with type A and AB thymoma, which is closely linked toGTF2Imutation. However, not much is known regarding the molecular genetics of this thymoma subtype. In this study, theGTF2Imutation status was investigated in 16 cases of micronodular thymoma.Methods16 micronodular thymomas were retrieved and the GTF2I mutation was tested by Sanger sequencing. The clinicopathological findings were documented.ResultsGTF2I c.1271T>A p.(Leu424His) mutation within exon 15 was detected in 14 out of 16 tumours (87.5%). Two patients died of other causes while all others remained alive with no evidence of recurrence during the follow-up period ranging from 19 to 188 months (median: 100 months).ConclusionsGTF2I mutation status and presence of spindle cell morphology may indicate that type A and AB thymoma, and micronodular thymoma represent a group biologically distinct from type B thymomas, which generally lack this mutation.