M dwarf stars are excellent candidates around which to search for exoplanets, including temperate, Earth-sized planets. To evaluate the photochemistry of the planetary atmosphere, it is essential to characterize the UV spectral energy distribution of the planet’s host star. This wavelength regime is important because molecules in the planetary atmosphere such as oxygen and ozone have highly wavelength-dependent absorption cross sections that peak in the UV (900–3200 Å). We seek to provide a broadly applicable method of estimating the UV emission of an M dwarf, without direct UV data, by identifying a relationship between noncontemporaneous optical and UV observations. Our work uses the largest sample of M dwarf star far- and near-UV observations yet assembled. We evaluate three commonly observed optical chromospheric activity indices—Hα equivalent widths and log10 L Hα /L bol, and the Mount Wilson Ca ii H&K S and indices—using optical spectra from the HARPS, UVES, and HIRES archives and new HIRES spectra. Archival and new Hubble Space Telescope COS and STIS spectra are used to measure line fluxes for the brightest chromospheric and transition region emission lines between 1200 and 2800 Å. Our results show a correlation between UV emission-line luminosity normalized to the stellar bolometric luminosity and Ca ii with standard deviations of 0.31–0.61 dex (factors of ∼2–4) about the best-fit lines. We also find correlations between normalized UV line luminosity and Hα log10 L Hα /L bol and the S index. These relationships allow one to estimate the average UV emission from M0 to M9 dwarfs when UV data are not available.
IntroductionAn estimated 1.2 million Americans have indications for using antiretroviral pre-exposure prophylaxis (PrEP) to prevent HIV acquisition. For many of these at-risk individuals, the best opportunity to learn about and receive PrEP will be during routine visits to their generalist primary care clinicians. However, few generalist clinicians have prescribed PrEP, primarily because of practical concerns about providing PrEP in primary care settings. The experiences of specialized primary care clinicians who have prescribed PrEP can inform the feasibility of PrEP provision by generalists.MethodsDuring January to February 2015, 35 primary care clinicians at a community health centre in Boston that specializes in the care of sexual and gender minorities completed anonymous surveys about their experiences and practices with PrEP provision. Responses were analyzed with descriptive statistics.Results and discussionThirty-two clinicians (response rate=91%) completed the surveys. Nearly all clinicians (97%) had prescribed PrEP (median 20 patients, interquartile range 11–33). Most clinicians reported testing and risk-reduction counselling practices concordant with U.S. Centers for Disease Control and Prevention guidelines for PrEP. Clinicians indicated that patients using PrEP experienced medication toxicities infrequently and generally reported high adherence. However, some clinicians’ practices differed from guideline recommendations, and some clinicians observed patients with increased risk behaviours. Most clinicians (79%) rated PrEP provision as easy to accomplish, and 97% considered themselves likely to prescribe PrEP in the future.ConclusionsIn a primary care clinic with specialized expertise in HIV prevention, clinicians perceived that PrEP provision to large numbers of patients was safe, feasible and potentially effective. Efforts to engage generalist primary care clinicians in PrEP provision could facilitate scale-up of this efficacious intervention.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.