BackgroundKnowledge on human papillomavirus (HPV) genotype distribution in recurrent respiratory papillomatosis (RRP) is essential to assess the impact of HPV vaccine. It is provided information for Colombia.MethodsIn all, 189 RRP primary cases diagnosed between 1985 and 2009 were identified from 5 pathology laboratories of Cali and Medellin, Colombia. HPV DNA testing in 129 cases that fulfilled inclusion criteria (available paraffin blocks, amplifiable DNA, and confirmed histologic diagnosis of RRP) was performed by the SPF‐10/LiPA25 assay (version 1).ResultsOf all cases 36.1% were juvenile (<12 years old) and a majority of adults were males (p = .09); 95% of cases were HPV positive. HPV 6, 11, and 16 contributed to 69%, 27.1%, and 7.8% of all HPV positive cases. Twelve cases (9.3%) showed multiple infections; 8 of these were HPV 6 or 11 positive.ConclusionsHPV prophylactic vaccine including HPV 6 and 11 may have a major impact against RRP. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

HPV 16 and 18 genotypes were found in nearly 20% of HNSCC cases in Colombian patients. The impact of HPV vaccination for the prevention of HNSCC in this population deserves further evaluation.

Objective. Describe factors associated with aggressive forms of recurrent respiratory papillomatosis (RRP). Materials and methods. One hundred eighty-nine RRP cases diagnosed between 1985 and 2009 were identified in pathological records. HPV was detected by the SPF-10 method with broad spectrum primers, (version 1). Results. 113 patients had only one surgery (less aggressive) and 76, two or more interventions (more aggressive). The likelihood of aggressive lesions decreased with increasing age at diagnosis and HPV- 11 was associated with no significant increase in the risk of aggressiveness. Conclusions. The age at diagnosis was the main determinant of RRP aggressiveness.

Los escándalos empresariales y las crisis financieras han sido producto de la crisis de valores. En este contexto, se describe el papel que desempeña el contador en la construcción y mantenimiento de la confianza, la cual, se ha visto afectada por las acciones poco éticas desarrolladas en el mundo de los negocios. Por consiguiente, la imagen del contador da cuenta de los juicios sobre las profesiones que están sustentados sobre la base de los rumores, en vez de las responsabilidades que recaen sobre estos. Recalcando la importancia que juega la ética en la creación de confianza y la reputación del profesional.

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