Vigorous optimization of quantum gates has led to bipotent quantum architectures, where the optimized gates are available for some qubits but not for others. However, such gate-level improvements limit the application of user-side pulse-level optimizations, which have proven effective for quantum circuits with a high level of regularity, such as the ansatz circuit of the Quantum Approximate Optimization Algorithm (QAOA). In this paper, we investigate the trade-off between hardware-level and algorithm-level improvements on bipotent quantum architectures. Our results for various QAOA instances on two quantum computers offered by IBM indicate that the benefits of pulse-level optimizations currently outweigh the improvements due to vigorously optimized monolithic gates. Furthermore, our data indicate that the fidelity of circuit primitives is not always the best indicator for the overall algorithm performance; also their gate type and schedule duration should be taken into account. This effect is particularly pronounced for QAOA on dense portfolio optimization problems, since their transpilation requires many SWAP gates, for which efficient pulse-level optimization exists. Our findings provide practical guidance on optimal qubit selection on bipotent quantum architectures and suggest the need for improvements of those architectures, ultimately making pulse-level optimization available for all gate types.