Treatment with condroitin/glucosamin contributes to a lower decline in physical component while it had no influence on mental component of health-related quality of life in older adults with ostheoartritis.
r e v b r a s r e u m a t o l . 2 0 1 5;5 5(1):83-88 REVISTA BRASILEIRA DE REUMATOLOGIA w w w . r e u m a t o l o g i a . c o m . b r Brief communication Elderly Functional status Functional disability Quality of life a b s t r a c t Aims: This study aimed to assess the influence of pharmacotherapy on health-related quality of life of elderly with ostheoarthritis. Methods: Longitudinal study involving 91 older adults from both genders (Age: 70.36 ± 5.57 years) from EELO project with self-reported knee or hip ostheoartritis, confirmed by radiographic analysis. Data regarding pharmacotherapy was assessed by a structured questionnaire and the quality of life was analyzed by SF-36 questionnaire at the initial moment and two years thereafter. All domains from quality of life were grouped in physical and mental components for further data analysis. Results: A statistically significant decline in both physical and mental components of quality of life was observed (Wilcoxon test, p < 0.05). However, it was observed a slighted decline in physical components in group treated with chondroitin/glucosamine when compared to other groups, according to Kruskal-Wallis test (p = 0.007). On the other hand, it was not observed any influence of pharmacological treatment on mental components of healthrelated quality of life (p > 0.05). Conclusions: Treatment with condroitin/glucosamin contributes to a lower decline in physical component while it had no influence on mental component of health-related quality of life in older adults with ostheoartritis. 84 r e v b r a s r e u m a t o l . 2 0 1 5;5 5(1):83-88 Análise da influência da farmacoterapia sobre a qualidade de vida em idosos com osteoartritePalavras-chave: Osteoartrite Idoso Funcionalidade Incapacidade funcional Qualidade de vida r e s u m o Objetivos: Analisar a influência da farmacoterapia da osteoartrite na qualidade de vida de idosos. Métodos: Estudo longitudinal, do qual participaram 91 idosos de ambos os gêneros (idade: 70,36 ± 5,57 anos), integrantes do projeto Estudo sobre Envelhecimento e Longevidade (EELO), portadores de osteoartrite de quadril e/ou joelho, confirmada por análise radiográ-fica. Foram levantados dados sobre a farmacoterapia da osteoartrite mediante o uso de questionários estruturados e a qualidade de vida foi analisada pelo questionário SF-36, no momento inicial e dois anos após a coleta de dados. Os diferentes domínios da qualidade de vida foram agrupados em domínios físicos e mentais para posterior análise dos dados. Resultados: Foi observado um declínio estatisticamente significativo tanto nos componentes físicos quanto mentais da qualidade de vida dos indivíduos (teste de Wilcoxon, p < 0,05). Foi observado menor declínio no componente físico da qualidade de vida para os usuários de condroitina/glicosamina em comparação com o grupo tratado com anti-inflamatórios ou não tratado, segundo o teste de Kruskal-Wallis (p = 0,007). Por outro lado, não foi observada influência do tratamento farmacológico sobre o componente mental da qualidade de vida (p > 0,0...
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