Cognitive reappraisal reduces anxiety, but we know little about how socioeconomic status (SES) moderates this association. Drawing from developmental, affective, and health psychological frameworks, the present 2 studies investigated SES as a moderator of reappraisal and anxiety using performance-based (Study 1) and self-report (Study 1 and 2) measures of reappraisal; analyzing nonclinical (Study 1) and clinical (Study 2) symptoms of anxiety; and utilizing a small, laboratory-based study (Study 1) and a large-scale 9-year longitudinal study (Study 2). Across studies, findings showed that reappraisal predicted lower anxiety at low levels of SES but did not or less so at high levels of SES. These results were found for self-report measures of reappraisal; generalized across nonclinical and clinical symptoms of anxiety; and emerged both concurrently and prospectively across 9 years. Findings remained stable when controlling for a number of covariates, including age, gender, and race; were more robust for income than education; largely generalized across gender (except for a men-specific moderation effect for education in Study 2); and were directional such that SES did not moderate associations between anxiety and changes in reappraisal. These findings highlight the importance of considering socioeconomic context in the link between reappraisal and anxiety.