Colorectal adenocarcinoma with rhabdoid phenotype is extremely rare, and only 1 case of adenocarcinoma showing rhabdoid dedifferentiation has been reported. The authors present another case of cecal adenocarcinoma with prominent rhabdoid feature in a 66-year-old man. The 13-cm sized tumor consisted mainly of rhabdoid cells and partly of adenocarcinoma, and transition from adenocarcinoma to rhabdoid areas was noted. Ultrastructural analysis revealed intracytoplasmic aggregates of intermediate filaments in the rhabdoid cells. Adenocarcinoma cells were diffusely immunoreactive to cytokeratin 7 and AE1/3, but occasionally positive for vimentin. The rhabdoid cells were negative for cytokeratin 7, weakly/focally immunoreactive to AE1/3, and diffusely positive for vimentin. These results suggested that the rhabdoid cells were dedifferentiated adenocarcinoma. Analysis of the rhabdoid cells with molecular techniques is also presented.
The effects of grid cathode structure on a low-input-power inertial electrostatic confinement fusion (IECF) device were studied to achieve a high neutron production rate (NPR). An increase in geometric transparency of the grid cathode by decreasing the number of wire rings is known to mean that the recirculation ion current is increased. We expected that this increase would contribute to an increase in the NPR. However, our experimental results showed that the NPR in the low-input-power IECF device (V ¼ 10:0{30:0 kV, I ¼ 40:0 mA) increased by decreasing the transparency. We clarified this tendency by analyzing the equipotential lines near the grid. As a result, we found that the distortion of these lines near the grid was lessened by decreasing the transparency. Lessening the distortion of these lines, rather than increasing the in recirculation ion current, was effective in increasing the NPR in the low-input-power IECF device. In addition, we find that the effect of mitigating these lines depended on the applied voltage.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.