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more rapidly in middle-and low-income countries. The major complication of diabetes blindness, kidney failure, heart attacks, stroke, and lower limb amputation. Increasing population, aging, urbanization, sedentary lifestyles and increasing prevalence of obesity are increasing the number of people with diabetes mellitus. The Background: Worldwide, cataracts remain the leading cause of blindness, affecting approximately 18 million people. Study shown that cataracts occur in young age and 2 -5 times more frequently in patients with diabetes, thus the visual loss has a significant impact on the working population. With going through literature, it has been confirmed that cataracts are the most common cause of visual impairment in older-onset diabetic patients and the rate of cataract surgery is correspondingly high. This study aims to analyze the onset cataract in patients with or without diabetes. Methods:A comparative cross-sectional study was carried out in health camp organized by department of optometry Era University, Lucknow between 2017 and 2018. Within the context of this survey, 1066 eligible patients at least 30 years were randomly selected for interview. Demographic data including age and gender were obtained from all participants. Eligible subject referred to Rural Health Center of Era Lucknow Medical College for ophthalmic examination. Results: There were 1066 individuals included in the study. 5.1% in the age group 35 -40 and 100% in 41 -50 age group diabetics were having cataract but in the same age group, there was not a single healthy person diagnosed with cataract. The risk of cataract increased with increasing diabetes duration ≥ 5 years vs. diabetes < 2 years. Conclusion:As per the study, the early onset of cataracts in diabetes compared to nondiabetic. The risk of cataract associated with diabetes is highest at younger ages. Patients with diabetes are at an increased risk for cataracts.

BACKGROUND Generally, it is seen that SPECT/CT images are more useful than the planar images. We compared post-therapy 131 I imaging findings on planar and SPECT/CT scans to assess the clinical utility of SPECT/CT in management of patients with differentiated thyroid cancer. MATERIALS AND METHODS Post-therapy imaging was performed at 4-7 (when 5mR/hrs. exposure rate were observed by the survey meter) days after 131 I administration and all patients underwent whole-body scintigraphy and SPECT/CT scanning on the same day. A generalised McNemar 1 was used to determine to establish the agreement between planar whole-body imaging and SPECT/CT for the assignment of benign, equivocal and malignant findings. RESULTS In 44 patients, 32 of the 44 patients underwent postsurgical 131 I ablation of residual thyroid tissue and 12 of 44 patients, 2 patients were treated twice. Hence, a total of 46 scans were analysed. SPECT/CT helped to localise focal iodine uptake and characterise it as either normal or abnormal thereby reducing the need for additional imaging studies. In post-thyroidectomy patients, SPECT/CT findings affected the ATA risk classification with implications for management by changing the interval for clinical followup and the need for additional imaging and laboratory tests. Our study found an 11% change in nodal status in the postsurgical group. Change in patient management was observed in 18%. CONCLUSION SPECT/CT enabled more accurate characterisation of focal iodine accumulation in patients.

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