The human bones are categorized based on elemental micro architecture and porosity. The porosity of the inner trabecular bone is high that is 40-95% and the nature of the bone is soft and spongy whereas the cortical bone is harder and is less porous that is 5 to 15%. Osteoporosis is a disease that normally affects women usually after their menopause. It largely causes mild bone fractures and further stages lead to the demise of an individual. The detection of Osteoporosis in Lumbar Spine has been widely recognized as a promising way to frequent fractures. Therefore, premature analysis of osteoporosis will estimate the risk of the bone fracture which prevents life threats. The paper is systematized in two different sections to classify normal (non-osteoporosis) and abnormal(osteoporosis)Lumbar spine trabecular bone. In this method, the first section is based on discriminating the lumbar spine trabecular bone micro-architecture predisposing by means of first and second order directional derivative of Laplacian of Gaussian filter with different standard deviation to acquire the minimum and maximum responses. The dimension reduction of texture features, quantization and adjacent scale coding with weighted multipliers are used to lessen the intensity variations of texture features. The second section is based on the reduction of histogram features as a training data set for classification of normal and osteoporotic images of lumbar spine (L1-L4) using K-Nearest Neighborhood (KNN) classifier. The tested dataset result gives effective classification accuracy of 97.22% with lesser texture feature dimension. The usage of weight multiplier as well as quantization technique plays a major role for the improvement of accuracy to diagnose osteoporosis for an input noisy and noiseless image.

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<p class="abstract">The human bones are categorized based on elemental micro architecture and porosity. The porosity of the inner trabecular bone is high that is 40-95% and the nature of the bone is soft and spongy where as the cortical bone is harder and is less porous that is 5 to 15%. Osteoporosis is a disease that normally affects women usually after their menopause. It largely causes mild bone fractures and further stages lead to the demise of an individual. This analysis is on the basis of bone mineral density (BMD) standards obtained through a variety of scientific methods experimented from different skeletal regions. The detection of osteoporosis in lumbar spine has been widely recognized as a promising way to frequent fractures. Therefore, premature analysis of osteoporosis will estimate the risk of the bone fracture which prevents life threats. This paper focuses on the advanced technology in imaging systems and fracture probability analysis of osteoporosis detection. The various segmentation techniques are explored to examine osteoporosis in particular region of the image and further significant attributes are extracted using different methods to classify normal and abnormal (osteoporotic) bones. The limitations of the reviewed papers are more in feature dimensions, lesser accuracy and expensive imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI), and DEXA. To overcome these limitations it is suggested to have less feature dimensions, more accuracy and cost-effective imaging modality like X-ray. This is required to avoid bone fractures and to improve BMD with precision which further helps in the diagnosis of osteoporosis.</p>

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Osteoporosis is a silent bone disease characterized by low bone mass and loss of bone tissue that may lead to weak and fragile bones and decreases in bone strength which increases the risk of fractures.It is more common in women rather than men. DEXA that is Dual Energy X-ray Absorptiometry is a model to diagnose osteoporosis although its low-availability, expensive, and high radiation exposure. The CAD (Computer-Aided Diagnosis) has enhanced the analysis to a higher level. The advanced learning paradigm that is Deep-Learn, Machine-Learn and Artificial Intelligence has exposed a turning point in the medical field which leads to accurate diagnosis of osteoporosis. The review is based on various anatomical sites such as lumbar spine, hip, forearm, calcaneus, and dental are assisted and examined based on validation, pre-trained networks, and accuracy. The combination of clinical data and images are fed to deep leaning models specifically CNN-Convolutional Neural Network, RNN-Recurrent Neural Network may result in completely automatic detection and diagnosis of osteoporosis.