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a ----------------------------------------------- ABSTRACT:Introduction: Diabetes mellitus is a type of metabolic disorder characterized by hyperglycemia resulting from defect in insulin secretion, insulin action or both. This study intended to compare High Density Lipoprotein Cholesterol (HDL) and Low Density Lipoprotein Cholesterol (LDL) profile between type II diabetic and non-diabetic subjects and also find the correlation between HDL and LDL cholesterol in type II diabetic. Methods: The study was conducted on 100 total subjects out of which experimental group with 50 subjects of known Type II Diabetes mellitus and control group with 50 subjects. Results: The result of the present study suggests that fasting blood sugar and LDL cholesterol levels were increased but HDL cholesterol level was reduced in type II diabetic subjects when compared to controls. Conclusion:The estimation of HDL cholesterol and LDL cholesterol in type II diabetes mellitus is very useful as it may serve as a useful parameter to monitor the prognosis of the patient.

Background: Pregnancy is a complex endocrine-metabolic adaptation and diabetogenic condition involving impaired cellular insulin sensitivity, increased β-cell function, and moderate elevation of blood glucose level. The threshold for a positive glucose challenge test (GCT) necessitating further diagnostic testing remains controversial in gestational diabetes mellitus (GDM). Aims & Objective: To find the association of risk factors with GDM, to evaluate the diagnostic value of GCT as compared to oral glucose tolerance test (OGTT) in GDM, and also to determine the optimal cutoff value of GCT with best sensitivity and specificity for the prediction of GDM and also to find the association of GCT between FBS and 2 nd hour OGTT glucose level.