No abstract

There is growing evidence that maternal prenatal stress may be hazardous to infant health. Changes in maternal hormonal and immune function as a result of stress may adversely affect the immune function and neurodevelopment of the fetus. Prenatal stress in the mother may produce lasting effects on the (1) infant's health status, (2) development and function of the infant's immune system, and (3) neurocognitive development of the infant. This article provides a synthesis of current human and animal literature on the effects of maternal prenatal stress on the developing fetus and the infant, with the resulting model evolving out of the framework of psychoneuroimmunology. The intent of the authors is an integrative review. The authors examined the following research question: What effect does maternal prenatal stress have on infants' immune development and neurodevelopment? All relevant studies were reviewed with no exclusion criteria. Major databases (CINAHL, MEDLINE, PsychINFO) were searched using a combination of the following key words: prenatal stress, cytokines, thymus, and infant neurodevelopment.

No abstract

This study was an initial psychometric test of the Chinese versions of the Index of Nausea, Vomiting and Retching (INVR), and the Prenatal Self-Evaluation Questionnaire (PSEQ) in pregnant Taiwanese women. Although there already is evidence that the English-language versions of the scales are reliable and valid, it is important to verify the proper psychometric characteristics of the Chinese versions. Forward and backward translation, and a multiphase instrumentation study describing internal consistency, test-retest reliability, and content validity of the translated versions were conducted. A convenience sample was recruited from prenatal clinics in the south of Taiwan. Three measurement instruments were used in this study: the demographic inventory (DI), the INVR, and the PSEQ. Thirty pregnant women participated in the study. Both the internal consistency and stability coefficients of the INVR and PSEQ were satisfactory. The indices of content validity (CVI) for the Chinese versions of these two instruments were both 1.0, indicating that they are acceptable for use among Taiwanese pregnant women. This was the first instrumentation study of the INVR and PSEQ applied to Taiwanese pregnant women. Researchers could use this study as a model for future translation and application of psychometric instrumentation.