PURPOSESacrococcygeal pilonidal disease is a source of one of the most common surgical problems among young adults. While male gender, obesity, occupations requiring sitting, deep natal clefts, excessive body hair, poor body hygiene and excessive sweating are described as the main risk factors for this disease, most of these need to be verified with a clinical trial. The present study aimed to evaluate the value and effect of these factors on pilonidal disease.METHODPreviously proposed main risk factors were evaluated in a prospective case control study that included 587 patients with pilonidal disease and 2,780 healthy control patients.RESULTSStiffness of body hair, number of baths and time spent seated per day were the three most predictive risk factors. Adjusted odds ratios were 9.23, 6.33 and 4.03, respectively (p<0.001). With an adjusted odds ratio of 1.3 (p<.001), body mass index was another risk factor. Family history was not statistically different between the groups and there was no specific occupation associated with the disease.CONCLUSIONSHairy people who sit down for more than six hours a day and those who take a bath two or less times per week are at a 219-fold increased risk for sacrococcygeal pilonidal disease than those without these risk factors. For people with a great deal of hair, there is a greater need for them to clean their intergluteal sulcus. People who engage in work that requires sitting in a seat for long periods of time should choose more comfortable seats and should also try to stand whenever possible.

We believe that soldiers coming from different regions of Turkey and candidates applying for auxiliary staff positions provide a small sample group resembling a representation of the whole of Turkey.

Laparoscopic cholecystectomy is a safety, efficacy,established method for the treatment of symptomatic gallstone disease. We aim to share traditional laparoscopic cholesistectomy experience and complications that treated with experienced surgeons in low-volume hospitals. This study was performed during the period of 2009-2011 in three hospital. We analyzed retrospectively 266 patients, who were operated elective by three surgeon whose experiences were closely. We compared demographic data, patients age, gender, number of ports, operation time, length of hospital stay, whether or not previous abdominal surgery, whether or not systemic disease, whether or not has been performed ERCP, reason of converted from laparoscopic to open cholecystectomy and complications. 266 [165 (%72,6) female and 101 (%27,4) male] patients evaluated retrospectively. The average age was 42,6 (range 27-42). The average duration of operation was 45 minutes (range 35-72). The operation was performed by using four ports in 195 (73,3%) patients and by using three ports in 71 (26,7%) patients. 25 (9,4%) patients had intra-abdominal drainage. ERCP was performed preoperatively in 5 (9,4%) patients. We convert open cholecystectomy in6 (2,3%) patients, due to bleeding, in 4 patients (1,5%) due to anatomical mismatch, 3 patients (1,1%) due to adhesions and difficult technical conditions. Laparoscopic cholecystectomy can be performed seamlessly with appropriate patient selection in low-volume hospitals, We believe that multidisciplinary approach was a priority in case with complications, it will be useful in terms of patient morbidity and mortality. Keywords: Cholecystectomy; laparoscopic; clinical outcome. ÖzetMorbiditesi %0,1 lere kadar indirilen, düşük volümlü hastanelerde uygulanabilen, ciddi komplikasyonları ancak tecrübeli cerrahlarca tedavi edilen geleneksel LK tecrübelerimizi, komplikasyonlarımızı, ne seviyede olduğumuzu görmeyi ve paylaşmayı amaçladık. Ocak 2008-Haziran 2011 tarihleri arasında 3 ayrı merkezde, 3 ayrı laparoskopik tecrübeleri birbirine yakın cerrah tarafından elektif şartlarda yapılan Laparoskopik Kolesistektomi olgularının pre-intra-post operatif bulgularına ulaşılarak, demografik verileri, operasyon endikasyonları, operasyon şekli (port sayısı, süresi), daha önce operasyon geçirip geçirmediği, Sistemik bir hastalığı olup olmadığı, hastanede yatma süreleri, açığa dönüş sebepleri, ERCP yapılıp yapılmadığı, görülen komplikasyonlar retrospektif olarak incelendi. 165 (%72.6)' i kadın, 101 (%27.4)' i erkek 266 hasta dosyası retrospektif olarak incelendi. Yaş ortalaması 42.6 yıl (range:24-72) idi. Ortalama operasyon süresi 45 dakika (range:30-75) bulundu. 71 (%26.7) hastada 3 port, 195 (%73,3) hasta 4 port kullanılarak operasyon gerçekleştirildi. 25 (%9.4) hastaya batın içi dren kondu. 5 (%9.4) hastaya preoperatif olarak ERCP yapılmış, 6 (%2.3) hasta daha önce üst batın, 31(%11.7) hasta da alt batın operasyonu geçirmiş olduğu bulundu. 6 (%2.3) hastada kanama, 4 hastada (%1.5) anatominin ortaya konamaması (anatomik uyums...

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PURPOSE:To evaluate the effects of platelet rich plasma (PRP) on the healing of fascia wherein peritonitis has been created. METHODS:Twenty eight Wistar Albino rats were divided into four groups. Only a primary fascial repair following laparotomy was performed on Group 1, a primary fascial repair performed and PRP treatment applied following laparotomy on Group 2, and a fecal peritonitis created following laparotomy and a primary fascial repair carried out on Group 3. A fecal peritonitis was created following laparotomy and primary fascial repair and PRP treatment on the fascia was carried out on Group 4. RESULTS:TNF-α was found to be significantly lower in the control group (Group 1). It was detected at the highest level in the group in which fecal peritonitis was created and PRP applied (Group 4). TGF-β was determined as being significantly higher only in Group 4. Histopathologically, the differences between the groups in terms of cell infiltration and collagen deposition were not found to be significant. CONCLUSION:When platelet rich plasma was given histologically and biochemicaly as wound healing parameters cellular infiltration, collagen accumulation, and tissue hydroxyiproline levels were not increased but neovascularization, fibroblast activation and TNF Alfa levels were increased and PRP accelerated wound healing.