Spider bites are commonly reported from many parts of the world. Clinical manifestations of spider bites reported range from simple local irritations and dermonecrotic lesions to potentially lethal neurotoxicity and intravascular hemolysis. In Agada Tantra, spider envenomation is coined as Luta visha (~spider bite poisoning), and a detailed description of different types of spider bites with their treatment is available in the literature. A 28-year-old female with a history of spider envenomation, presented with two reddish lesions with pale blue depression at the center associated with pain, burning sensation, and itching on the dorsum of her left leg. The lesion was a fast-progressive necrotic lesion and was diagnosed as Pitta-kapha predominant manifestation due to the spider bite. She was administered Guduchyadi kashayam (15 mL) and Vilwadi agada (1000 mg) thrice daily and external Shatadhouta ghrita application after washing with Triphala kashaya. On the fifth day of the bite, when the pain increased and was associated with a mild fever, Sooryaprabha gutika (125 mg) thrice daily was given. The lesion was fully necrosed by the seventh day of the bite. The necrosed tissue was removed, and Mahatiktaka ghrita was applied. By the 17th day of the bite, the wound was healed with no pain on palpation. After 21 days of bite, all the medications were stopped. Dooshivishari agada (500 mg) and Haridrakhandam (5 g) twice daily were prescribed to eliminate residual poison, if any. Eladi kera thailam was administered externally to reduce the blackish discoloration of the bite site. This fast-progressive necrotic lesion was solely managed by Ayurvedic medicines.
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