This study involved establishing a lifestyle scale that addresses wellness tourism. Seventy-five items were collected and scored by experts; subsequently, 50 items were incorporated in the question bank for composing a questionnaire. The surveyed tourists returned 1,506 valid questionnaires. Finally, by using factor analyses, 26 items and 7 factors were extracted to design a wellness lifestyle scale; the conceptual framework for a wellness lifestyle was then constructed for local tourists in Taiwan. Future researchers of market segmentation in wellness tourism can conduct validation based on the proposed scale, screening potential customers in the wellness tourism market.