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To evaluate an adhesive tape containing 60% lidocaine (Penles(R)), we used a pain thermometer and pressure algometer to measure pain thresholds of superficial and deep pain in 20 adult volunteers to whose arms a 60% lidocaine tape or placebo tape was applied. The tapes were put on the forearms of volunteers, and pain thresholds were measured before and 15, 30, 60, 90, 120 min after application. In the lidocaine tape group, the threshold of superficial pain significantly increased compared to the placebo tape group after 60 and 90min. The deep pain threshold increased significantly in both the lidocaine and placebo tape groups, but no significant difference was observed between them. An adhesive tape containing 60% lidocaine is useful for reducing superficial pain, but we were unable to prove any effect on deep pain threshold within 120min after application of the tape.

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