Maintenance of core temperature is a major component of 24-h energy expenditure, and its dysregulation could contribute to the pathophysiology of obesity. The relationship among temperature, sex, and BMI, however, has not been fully elucidated in humans. This study investigated core temperature in obese and lean individuals at rest, during 20-min exercise, during sleep, and after food consumption. Twelve lean (18.5-24.9 kg/m(2)) and twelve obese (30.0-39.9 kg/m(2)) healthy participants, ages 25-40 years old, were admitted overnight in a clinical research unit. Females were measured in the follicular menstrual phase. Core temperature was measured every minute for 24 h using the CorTemp system, a pill-sized sensor that measures core temperature while in the gastrointestinal tract and delivers the measurement via a radio signal to an external recorder. Core temperature did not differ significantly between the obese and lean individuals at rest, postmeals, during exercise, or during sleep (P > 0.5), but core temperature averaged over the entire study was significantly higher (0.1-0.2 °C) in the obese (P = 0.023). Each individual's temperature varied considerably during the study, but at all times, and across the entire study, women were ~0.4 °C warmer than men (P < 0.0001). These data indicate that obesity is not associated with a lower core temperature but that women have a higher core temperature than men at rest, during sleep, during exercise, and after meals.
Objective
Weight gain during the menopausal transition is common. Although
studies have suggested that weight gain is more likely related to aging than
menopause, there is a reduction in resting energy expenditure with surgical
or natural menopause which is independent of age and changes in body
composition. The underlying mechanisms could include a reduction in core
body temperature.
Methods
Data were obtained from two related studies. Sample size was 23 men
and 25 women (12 premenopausal,13 postmenopausal). In the Clinical Research
Unit, core temperature was measured every minute for 24 hours (CorTemp
System,HQ Inc.).
Results
Mean 24-hour core body temperature was 0.25 ± 0.06 °C
lower in postmenopausal than premenopausal women (p=0.001). Mean
24-hour core temperature was 0.34 ± 0.05 °C lower in men
than in premenopausal women (p<0.001).
Conclusions
Postmenopausal women, like men, had lower core body temperatures than
premenopausal women. This may have implications for midlife weight gain.
Inpatients who recognize that they are overweight or obese are interested in pursuing weight-loss initiatives. Despite their interest, most do not receive weight-loss interventions while hospitalized.
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