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Objective: Patients with end-stage renal disease (ESRD) has experienced poorer quality of life (QoL). The present study aimed to evaluate the effects of psychotherapy on QoL among patients with ESRD. Methods: We conducted a systematic search for studies in MEDLINE, PubMed, and SAGE Journals databases from inception up to 10 April 2020. The inclusion criteria were studies with randomized controlled trial (RCT) design, patients with kidney disease, published in English language, and had full-text content. Two researchers independently conducted the extraction on the articles among patients with ESRD and also evaluated quality of each study. A random-effects meta-analysis was conducted, and data was presented in weighted mean difference (WMD) with 95% confidence interval (CI). Results: Eight studies were included in the systematic review and five were entered for metaanalysis. Compared with control group, the intervention group showed a significant difference for QoL, in both physical component summary (PCS) (WMD: 2.52 [95% CI: 0.48, 4.57]) and mental component summary (MCS) (WMD: 4.22 [95% CI: 1.54, 6.89]). The heterogeneity across studies for both PCS and MCS was found to be I 2 = 0%. Conclusion: The findings support that psychotherapy could improve QoL among patients with ESRD, as compared to control group. Therefore, psychotherapy should be considered as an essential component in improving ESRD patients’ health.

Objectives: This systematic review aims to identify influencing factors of medication adherence behavior in patients with end-stage renal disease (ESRD), with a special interest in patient-related factors based on the World Health Organization adherence model. Materials and Methods: Primary electronic databases comprising PubMed, Scopus, Web of Science, Embase and Cochrane Library, as well as ProQuest (Health and Medical), ProQuest (Psychology), and EBSCOHost (APA PsychARTICLES) were used to search for literature on patient-related factors in medication adherence, from inception till August 31, 2021. Results: 479 articles were identified and six articles meeting eligibility criteria were reviewed and remained in this systematic review. The present review found that despite different tools being used to measure ESRD's perception of medication's necessity and beliefs, there was a profound association between perception and beliefs with medication adherence behavior. There is a positive relationship between knowledge, belief, educational level, ethnicity, female, and medication adherence behavior. Mixed finding was reported between perception, age, and medication adherence behavior. However, there were no studies on patients' attitudes and medication adherence behavior as suggested in the WHO adherence model. Conclusion: Only a limited number of patient-related factors were available for evaluation in the current systematic review. Additional research is needed to advance the understanding of medication adherence behavior affected by patient-related factors on the medication and illness. However, the findings must be taken with caution because of the limited studies included in this review.