I n 2017, a total of 9,093 new cases of active tuberculosis (TB) were reported in the United States, and ≈4.5% of these occurred in persons experiencing homelessness (PEH) in the year preceding their diagnosis (1). The incidence of TB in PEH populations is >10 times that of the general population (i.e., 36-47 vs. 2.8 cases/100,000 population during 2006-2010) (2) because risk factors, such as HIV infection, mental illness, substance abuse, and barriers to accessing healthcare, put them at higher risk. In addition, PEH often use homeless shelters, and congregate in