Primary skin melanoma and skin cancers have been more prevalent in the previous decades and therefore have become a very significant public health problem. Dermatologists of the Skin and Venereal Diseases Clinic of the University of Sarajevo Clinics Centre initiated the first public preventive action called "Days of Fighting Melanoma" in May 2008. The objective of the campaign was to provide free dermatological examinations to all volunteers and to inform, through the media, wider population on early signs and recognition of skin cancer and the importance of sun protection. The total of 325 citizens were examined clinically and with dermatoscope in the period between 5 and 31 May 2008. The examination also included histological diagnoses: 7 patients with confirmed melanoma, 30 with basal cell carcinoma and 2 with spinocellular carcinoma. The results suggested a need for the expansion of the campaign to other towns in our country in order to demonstrate the importance of early detection of the disease and treatment options.
Aim of the studyExposure to radiation and aging are the leading causes of breast cancer among female patients. We aimed to investigate and assess the relationship between exposure to medical, diagnostic and iatrogenic radiation and breast cancer using a questionnaire among 100 newly diagnosed female breast cancer patients and 100 control female subjects without cancer.Material and methodsA case control study using a family ambulatory based survey was conducted among 200 female patients from all municipalities of Zenica-Doboj Canton. New cases of breast cancer among subjects of experimental groups (n = 100) were diagnosed between 1 January 2003 and 31 December 2007 using the institutional clinical procedure for breast cancer diagnosis. Data were obtained using a self-rated questionnaire on radiation as a breast carcinogen. Data analysis was performed using SPSS version 19.0.ResultsThere were no significant differences between the two groups and their subgroups for individual data and demographics except for prevalence of decreased family financial situation (practical poverty) among subjects with breast cancer in relation to control subjects (31%: 17% among control subjects; p = 0.001). Female patients who are exposed to iatrogenic radiation before the 3rd year of life (OR = 1.29; 95% CI: 0.839–1.985) and those who are exposed to CT more than twice per year are more than twice as likely to have breast carcinoma (OR = 2.02; 95% CI: 1.254–3.261) compared to control subjects. Poverty and low family income are vulnerability factors associated with elevated levels of breast carcinoma. This result is not in accordance with prior study results.ConcIusionsIt is necessary to develop an adequate registration system of iatrogenic exposure to radiation for each patient of any age, particularly for children aged < 3 years and for CT iatrogenic exposure.
Dermoscopy is valid, noninvasive technique for the visualization of different morphological structures within pigmented melanocytic skin lesion. In clinical practice, positive personal history is considered to be as an indication of increased melanoma risk. The thickness of melanoma (Breslow Index) is the most important independent predicting factor of survival for stage I patients. We aimed to present a two cases of head-melanoma and discuss prominent clinical and dermoscopic features across the spectrum of "hidden-melanoma" and differential diagnosis. StreszczenieDermoskopia to aktualnie, nieinwazyjna metoda wizualizacji różnych struktur morfologicznych w obrębie melanocytowych zmian skórnych. W praktyce klinicznej, dodatni wynik badania jest uznawany z wskaźnik podwyższonego wystąpienia czerniaka. Grubość czerniaka (Indeks Breslow) jest najważniejszym niezależnym czynnikiem prognostycznym dla długości przeżycia u pacjentów w I stopniu zaawansowania choroby. Postaraliśmy się przedstawić dwa przypadki czerniaka okolicy skóry głowy i przedyskutować ważne kliniczne i dermoskopowe cechy pod kątem "ukrytych czerniaków" oraz diagnostyki różnicowej.
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