Three new cembrane-type diterpenoids, lobophynins A
(1), B (2), and C (3), were isolated
from
the soft coral Lobophytum
schoedei. Their
structures and relative stereochemistries were
determined by extensive 2D NMR studies. Lobophynin C
(3) has ichthyotoxicity against the
mosquito fish, Oryzias
latipes, and lethal
activity toward brine shrimps.
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